The first leg match in Italy finished, 2-2; Tottenham made a comeback from 0-2 down to grab an advantage.
Juventus must score to advance to the quarter finals as Tottenham club currently has the away goals upper hand.
The other match of the evening will see Manchester City taking on Basel in Manchester, as the English club defeated its opponent, 4-0, in the first leg match.
On Tuesday, Real Madrid eliminated Paris Saint Germain on a, 5-2, aggregate in two matches; Madrid defeated their opponent, 2-1, in Paris.
Tuesday's other matchup saw Liverpool and Basel draw, 0-0, and Liverpool advanced to quarter finals as they defeated their opponent, 5-0, in the first leg.