Injuries leave Sahin, Ozyakup and Kaya unavailable for Turkey's first Euro 2016 qualifier against Iceland.
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Turkish national football team will start its UEFA Euro 2016 qualifiers Group A campaign against Iceland on Tuesday.
The match, which will be refereed by Ivan Bebek of Croatia, kicks off at 7:45 p.m. GMT at Laugardalsvollur Stadium in the Icelandic capital, Reykjavik.
Turkey will be without midfielders Nuri Sahin and Oguzhan Ozyakup, and centre-back Semih Kaya due to injuries.
In other Group A showdowns, Czech Republic will host group favorites Netherlands, while underdogs Kazakhstan will face Latvia.